Things to Know About Pharmacokinetics: Drug Discovery & Development

drug discovery and drug development

Pharmacokinetics (PK) is the analysis and description of the disposition of a drug in the body, encompassing development of the mathematical description of all dispositional processes in the body, defined as ADME – absorption, distribution, metabolism, and elimination. Closely related fields in the biochemical pharmacology discipline include clinical pharmacokinetics, pharmacodymamics, pharmacology, and toxicokinetics.

Pharmacokinetics definition  is the analysis and description of the disposition of a drug in the body, encompassing development of the mathematical description of all dispositional processes in the body, defined as ADME – absorption, distribution, metabolism, and elimination. Pharmacokinetics describes what the body does with a particular drug. Simply put, pharmacokinetics (PK) is the analysis and description of the disposition of a drug in the body. It encompasses development of the mathematical description of all dispositional processes in the body, defined as ADME – absorption, distribution, metabolism, and elimination. Pharmacokinetics is the study of how an organism affects a drug. It is concerned with the absorption, distribution, localization in the organism, biotransformation (metabolism, chemical modifications) and excretion of chemicals administered to a living organism. The word pharmacokinetics comes from two words in Greek and Latin: pharmakon “drug” and kinetikos “moving, putting in motion.”

 Pharmacokinetics is a branch of pharmacology dedicated to determine the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. 

How long do you think it takes for a new drug to get approved in the US? About 12-15 years, that’s roughly 1/3rd duration of the entire professional career for any of us. Next, how much investment do you think is required to bring a new drug to market? ~$1 Billion, that’s equivalent to employing 665+ employees at the annual salary of $100k for 15 years. Simply put, approval of a new drug discovery and drug development is a massive undertaking and selecting the right partners, who prioritize in sync with you and focus on high quality and fast turnaround, goes a long way in avoiding missteps and moving your drug program closer to success. Simply put, approval of a new drug is a massive undertaking and selecting the right partners, who prioritize in sync with you and focus on high quality and fast turnaround, goes a long way in avoiding missteps and moving your drug program closer to success.

At NorthEast BioLab, we offer competitive pricing and high quality without sacrificing speed. We help you get closer to success by selecting partners who prioritize in sync with you and focus on high quality and fast turnaround. Feel free to schedule a call to learn more about how we support our customers through each step of the drug development process. The NorthEast BioLab, Inc is a preclinical biopharmaceutical research company providing services to the pharmaceutical and biotechnology industries, as well as universities and private researchers. We offer four primary service areas: Discovery Studies, Lead Development, Toxicology and Manufacturing Services. We also provide complementary in vivo imaging services.

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